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Fibrinogen
🥰Excellent
Catalog No. T78367Cas No. 9001-32-5
Fibrinogen is a heterodimeric protein that can be cleaved by thrombin. Fibrinogen is a potential marker for cardiovascular disease and plays an important role in metabolism. Its absence can cause fibrinogenemia.
Fibrinogen
Fibrinogen
🥰Excellent
Catalog No. T78367Cas No. 9001-32-5
Fibrinogen is a heterodimeric protein that can be cleaved by thrombin. Fibrinogen is a potential marker for cardiovascular disease and plays an important role in metabolism. Its absence can cause fibrinogenemia.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | $40 | In Stock | |
| 500 mg | $92 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Fibrinogen is a heterodimeric protein that can be cleaved by thrombin. Fibrinogen is a potential marker for cardiovascular disease and plays an important role in metabolism. Its absence can cause fibrinogenemia. |
| In vitro | Confluent MVECs were serum starved for 16 h and incubated with one of the following: Fibrinogen (2 or 4 mg/ml), Fibrinogen (4 mg/ml) with antibody against ICAM-1 (50 μM), Fibrinogen (4 mg/ml) with antibodies against α5 and β1, or β3 integrins (50 μM each), or Fibrinogen (4 mg/ml) with MEK inhibitors PD98059 or U0126 (50 μM each) at 37°C for 30 min. Fibrinogen induced a distinct dose-dependent increase of ERK phosphorylation that was significantly decreased by the presence of MEK inhibitors, PD98059 or U0126. Treatment of ECs with PD98059 (0.44 ± 0.03 FIU/cell, n = 4) or U0126 (0.40 ± 0.02 FIU/cell, n = 4), did not alter ERK phosphorylation in ECs compared to that in the control group (0.50 ± 0.05 FIU/cell, n = 4). [1] |
| Cas No. | 9001-32-5 |
Storage & Solubility Information
| Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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