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Peptidesα-Conotoxin Vc1.1 TFA
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α-Conotoxin Vc1.1 TFA

α-Conotoxin Vc1.1 TFA
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α-Conotoxin Vc1.1 TFA

Catalog No. T73894
α-Conotoxin Vc1.1 TFA, a disulfide-bonded peptide derived from Conus victoriae, selectively antagonizes nAChRs. It effectively inhibits the α3α5β2, α3β2, and α3β4 nAChR subtypes with IC50 values of 7.2 μM, 7.3 μM, and 4.2 μM, respectively, while exerting minimal inhibition on other nAChR subtypes. This compound shows promise for research into neuropathic pain. [1] [2]
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Product Introduction

Bioactivity
Description
α-Conotoxin Vc1.1 TFA, a disulfide-bonded peptide derived from Conus victoriae, selectively antagonizes nAChRs. It effectively inhibits the α3α5β2, α3β2, and α3β4 nAChR subtypes with IC50 values of 7.2 μM, 7.3 μM, and 4.2 μM, respectively, while exerting minimal inhibition on other nAChR subtypes. This compound shows promise for research into neuropathic pain. [1] [2]
Chemical Properties
Molecular Weight1921
FormulaC73H104F3N23O27S4
Cas No.
Storage & Solubility Information
Storagekeep away from moisture

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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