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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | Backorder |
Description | SKF 100398, also known as d(CH2)5Tyr(Et)VAVP, is a particular analog of arginine vasopressin (AVP). It acts as a specific antagonist, specifically targeting the antidiuretic effect caused by both exogenous and endogenous AVP. |
In vivo | SKF 100398 specifically counteracts the water-retention effect of both externally supplied and internally generated arginine vasopressin (AVP)[1]. At a dosage of 8 μg/kg administered intravenously, SKF 100398 effectively nullifies AVP’s antidiuretic action[1]. The study was conducted on male Sprague-Dawley rats weighing 250-300 g[1], demonstrating that this compound, when given intravenously at 8 μg/kg, completely inhibits the antidiuretic impact of externally administered AVP (4 ng/kg body wt i.v.). |
Alias | d(CH2)5Tyr(Et)VAVP |
Molecular Weight | 1136.4 |
Formula | C53H77N13O11S2 |
Cas No. | 77453-01-1 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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