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Extracellular Death Factor TFA (EDF TFA) is a linear pentapeptide that is produced and released by communicating cells and activates cell death pathways in cellular subpopulations when sufficient concentrations are reached.EDF TFA is sensitive to extreme pH, high temperatures, and other stressful conditions. At a concentration of 2.5 ng/ml, EDF has been shown to promote mazeEF (toxin-antitoxin system within bacteria) mediated cell death, promote the endonuclease activity of MazF toxin, lead to degradation of bacterial mRNA, and significantly reduce population size in E. coli cultures.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $43 | In Stock | |
5 mg | $98 | In Stock | |
10 mg | $143 | In Stock | |
25 mg | $238 | In Stock |
Description | Extracellular Death Factor TFA (EDF TFA) is a linear pentapeptide that is produced and released by communicating cells and activates cell death pathways in cellular subpopulations when sufficient concentrations are reached.EDF TFA is sensitive to extreme pH, high temperatures, and other stressful conditions. At a concentration of 2.5 ng/ml, EDF has been shown to promote mazeEF (toxin-antitoxin system within bacteria) mediated cell death, promote the endonuclease activity of MazF toxin, lead to degradation of bacterial mRNA, and significantly reduce population size in E. coli cultures. |
In vitro | Tryptophan may be a key residue in the hydroxyl radical scavenging activity of Extracellular Death Factor TFA, which can protect Escherichia coli from killing by bactericidal antibiotics but not from DNA damage or killing by bacteriostatic antibiotics. [1] |
Alias | Extracellular Death Factor TFA(960129-66-2 Free bse), EDF TFA |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO: 100 mg/mL, Sonication is recommended. ![]() |
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