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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $53 | In Stock | |
10 mg | $74 | In Stock | |
25 mg | $97 | In Stock | |
50 mg | $157 | In Stock | |
100 mg | $236 | In Stock | |
200 mg | $353 | In Stock | |
500 mg | $531 | In Stock | |
1 mL x 10 mM (in DMSO) | $85 | In Stock |
Description | Beta-Sheet Breaker Peptide iAβ5 Acetate (C33H43N5O8) inhibit amyloidogenesis in rat brain models. |
In vivo | 5-residue peptide that inhibits amyloid beta-protein fibrillogenesis, disassembles preformed fibrils in vitro and prevents neuronal death induced by fibrils in cell culture. In addition, the beta-sheet breaker peptide significantly reduces amyloid beta-protein deposition in vivo and completely blocks the formation of amyloid fibrils in a rat brain model of amyloidosis. These findings may provide the basis for a new therapeutic approach to prevent amyloidosis in Alzheimer's disease. |
Alias | Beta-Sheet Breaker Peptide iAβ5 Acetate(182912-74-9 Free base) |
Molecular Weight | 697.78 |
Formula | C35H47N5O10 |
Cas No. |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 60 mg/mL (94.08 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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