HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

Catalog No. TMPK-01280

Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.54 kDa and the accession number is XP_005571238.1.

HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

Catalog No. TMPK-01280

Pack Size	Price	Availability
100 μg	$418	7-10 days
500 μg	$1,670	7-10 days
1 mg	$2,800	7-10 days

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Product Information

Biological Activity	Immobilized Cynomolgus/Rhesus macaque Her3, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-Her3 Antibody, hFc Tag with the EC50 of 20.1ng/ml determined by ELISA.
Description	Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.54 kDa and the accession number is XP_005571238.1.
Species	Cynomolgus,Rhesus
Expression System	HEK293 Cells
Tag	C-His
Accession Number	XP_005571238.1
Synonyms	p85-sErbB3,p45-sErbB3,p180-ErbB3,MGC88033,MDA-BF-1,LCCS2,HER3c-erbB-3,HER3,ErbB-3,ERBB3
Construction	Ser20-His641
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	69.54 kDa (predicted). Due to glycosylation, the protein migrates to 85-105 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).