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Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μg | $498 | 7-10 days |
Biological Information | Kinase activity untested |
Description | EphA3 Protein, Mouse, Recombinant (aa 569-984, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 74.3 kDa and the accession number is EDK98238.1. |
Species | Mouse |
Expression System | Baculovirus Insect Cells |
Tag | His, GST |
Accession Number | EDK98238.1 |
Synonyms | ETK1,EPH receptor A3,Hek4,Mek4,AW492086,End3,Cek4,Hek,Tyro4 |
Construction | The Mouse EPHA3 (EDK98238.1) (Gly569-Val984) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus. |
Protein Purity | > 90 % as determined by SDS-PAGE |
Molecular Weight | 74.3 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Supplied as sterile 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 8.0. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage | It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice. |
Research Background | EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
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