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Resolvin D1
🥰Excellent
Catalog No. T13864Cas No. 872993-05-0
Alias RvD1
Resolvin D1 (RvD1) is an endogenous pro-inflammatory mediator that blocks pro-inflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α-mediated inflammation in macrophages, and enhances macrophage phagocytosis of apoptotic cells.
Resolvin D1
🥰Excellent
Catalog No. T13864Alias RvD1Cas No. 872993-05-0
Resolvin D1 (RvD1) is an endogenous pro-inflammatory mediator that blocks pro-inflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α-mediated inflammation in macrophages, and enhances macrophage phagocytosis of apoptotic cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg (265.6 µM * 250 μL in Ethanol) | $1,098 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Resolvin D1 (RvD1) is an endogenous pro-inflammatory mediator that blocks pro-inflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α-mediated inflammation in macrophages, and enhances macrophage phagocytosis of apoptotic cells. |
| In vivo | In 30 eight-week-old female DBA/1J mice (18-20 g) with collagen antibody-induced arthritis (CAIA), Resolvin D1 (100, 500, and 1000 nanograms; intraperitoneal injection;daily) exhibited reduced arthritis scores[3]. |
| Alias | RvD1 |
| Molecular Weight | 376.49 |
| Formula | C22H32O5 |
| Cas No. | 872993-05-0 |
| Smiles | [C@@H]([C@@H](/C=C/C=C/C=C\C=C\[C@H](C/C=C\CC)O)O)(C/C=C\CCC(O)=O)O |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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