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Fraxetin

🥰Excellent
Catalog No. T2909Cas No. 574-84-5
Alias 7,8-dihydroxy-6-methoxy coumarin

Fraxetin (7,8-dihydroxy-6-methoxy coumarin) has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a marked inhibitory effect on S.aureus proliferation. It increased the level of Nrf2/ARE, and HO-1, inhibit the formation of ROS, cytochrome c release, activation of caspase-3 and 9, and suppressed the up-regulation of Bax.

Fraxetin

Fraxetin

🥰Excellent
Purity: 99.76%
Catalog No. T2909Alias 7,8-dihydroxy-6-methoxy coumarinCas No. 574-84-5
Fraxetin (7,8-dihydroxy-6-methoxy coumarin) has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a marked inhibitory effect on S.aureus proliferation. It increased the level of Nrf2/ARE, and HO-1, inhibit the formation of ROS, cytochrome c release, activation of caspase-3 and 9, and suppressed the up-regulation of Bax.
Pack SizePriceAvailabilityQuantity
5 mg$43In Stock
10 mg$68In Stock
25 mg$123In Stock
50 mg$193In Stock
100 mg$313In Stock
1 mL x 10 mM (in DMSO)$48In Stock
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Purity:99.76%
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Product Introduction

Bioactivity
Description
Fraxetin (7,8-dihydroxy-6-methoxy coumarin) has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a marked inhibitory effect on S.aureus proliferation. It increased the level of Nrf2/ARE, and HO-1, inhibit the formation of ROS, cytochrome c release, activation of caspase-3 and 9, and suppressed the up-regulation of Bax.
Alias7,8-dihydroxy-6-methoxy coumarin
Chemical Properties
Molecular Weight208.17
FormulaC10H8O5
Cas No.574-84-5
SmilesCOc1cc2ccc(=O)oc2c(O)c1O
Relative Density.1.508g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 13 mg/mL (62.45 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.8038 mL24.0188 mL48.0377 mL240.1883 mL
5 mM0.9608 mL4.8038 mL9.6075 mL48.0377 mL
10 mM0.4804 mL2.4019 mL4.8038 mL24.0188 mL
20 mM0.2402 mL1.2009 mL2.4019 mL12.0094 mL
50 mM0.0961 mL0.4804 mL0.9608 mL4.8038 mL

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