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N-Bis(2-hydroxypropyl)nitrosamine

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COA HNMR

N-Bis(2-hydroxypropyl)nitrosamine

Catalog No. T19445Cas No. 53609-64-6

N-Bis(2-hydroxypropyl)nitrosamine (DHPN) is a carcinogenic agent.

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Pack Size	Price	Availability
5 mg	$30	In Stock
10 mg	$39	In Stock
25 mg	$73	In Stock
50 mg	$89	In Stock
100 mg	$139	In Stock
200 mg	$198	In Stock
1 mL x 10 mM (in DMSO)	$43	In Stock

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Related Compound Libraries of "N-Bis(2-hydroxypropyl)nitrosamine"

Product Introduction

Bioactivity

Description	N-Bis(2-hydroxypropyl)nitrosamine (DHPN) is a carcinogenic agent.
In vivo	The carcinogenic activity of orally administered N-bis(2-hydroxypropyl)-nitrosamine (DHPN) in male Wistar rats was evaluated with respect to its dose. DHPN was administered at two doses, 100 ppm and 500 ppm, in the drinking water to rats for 25 to 52 weeks. Tumors developed in the lung, liver, and thyroid of rats receiving 100 ppm DHPN and in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats receiving 500 ppm DHPN. The principal target organ was the lung in rats receiving either 100 or 500 ppm DHPN, indicating that the carcinogenic action of these doses of DHPN was similar to that of higher doses previously reported[2].
Alias	Di(2-hydroxypropyl)nitrosamine, DHPN, Diisopropanolnitrosamine

Chemical Properties

Molecular Weight	162.19
Formula	C6H14N2O3
Cas No.	53609-64-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 100 mg/mL (616.56 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.1656 mL	30.8280 mL	61.6561 mL	308.2804 mL
5 mM	1.2331 mL	6.1656 mL	12.3312 mL	61.6561 mL
10 mM	0.6166 mL	3.0828 mL	6.1656 mL	30.8280 mL
20 mM	0.3083 mL	1.5414 mL	3.0828 mL	15.4140 mL
50 mM	0.1233 mL	0.6166 mL	1.2331 mL	6.1656 mL
100 mM	0.0617 mL	0.3083 mL	0.6166 mL	3.0828 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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