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8-iso Prostaglandin F1α

Name: 8-iso Prostaglandin F1α
Brand: TargetMol
SKU: T36162
Rating: 4.5 (1 reviews)

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Catalog No. T36162Cas No. 26771-96-0

Alias 8-iso Prostaglandin F1α

8-iso PGF1α is an isoprostane that was first identified in human semen. It is a member of the isoprostane family, which are eicosanoids of non-cyclooxygenase origin. 8-iso PGF1α is present along with its 19-hydroxy congener at 5-10 μg/ml of seminal plasma.

8-iso Prostaglandin F1α

😃Good

Catalog No. T36162Alias 8-iso Prostaglandin F1αCas No. 26771-96-0

Pack Size	Price	Availability
1 mg	Inquiry	35 days
5 mg	Inquiry	35 days
10 mg	Inquiry	35 days

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Product Introduction

Bioactivity

Description	8-iso PGF1α is an isoprostane that was first identified in human semen. It is a member of the isoprostane family, which are eicosanoids of non-cyclooxygenase origin. 8-iso PGF1α is present along with its 19-hydroxy congener at 5-10 μg/ml of seminal plasma.
Alias	8-iso Prostaglandin F1α

Chemical Properties

Molecular Weight	356.503
Formula	C₂₀H₃₆O₅
Cas No.	26771-96-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMF: 50 mg/mL (140.25 mM), Sonication is recommended.

Ethanol: 50 mg/mL (140.25 mM), Sonication is recommended.

PBS (pH 7.2): 1 mg/mL (2.81 mM), Sonication is recommended.

DMSO: 50 mg/mL (140.25 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/DMF/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8050 mL	14.0251 mL	28.0503 mL	140.2513 mL

DMF/Ethanol/DMSO

	1mg	5mg	10mg	50mg
5 mM	0.5610 mL	2.8050 mL	5.6101 mL	28.0503 mL
10 mM	0.2805 mL	1.4025 mL	2.8050 mL	14.0251 mL
20 mM	0.1403 mL	0.7013 mL	1.4025 mL	7.0126 mL
50 mM	0.0561 mL	0.2805 mL	0.5610 mL	2.8050 mL
100 mM	0.0281 mL	0.1403 mL	0.2805 mL	1.4025 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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