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DSP Crosslinker

🥰Excellent
Catalog No. T15175Cas No. 57757-57-0

DSP Crosslinker, used in antibody-drug conjugates (ADCs) synthesis, is a cleavable ADC linker[1].

DSP Crosslinker

DSP Crosslinker

🥰Excellent
Purity: 97.89%
Catalog No. T15175Cas No. 57757-57-0
DSP Crosslinker, used in antibody-drug conjugates (ADCs) synthesis, is a cleavable ADC linker[1].
Pack SizePriceAvailabilityQuantity
25 mg$30In Stock
50 mg$39In Stock
100 mg$55In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:97.89%
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Product Introduction

Bioactivity
Description
DSP Crosslinker, used in antibody-drug conjugates (ADCs) synthesis, is a cleavable ADC linker[1].
In vitro
ADCs consist of an antibody attached to an ADC cytotoxin through an ADC linker.
Chemical Properties
Molecular Weight404.42
FormulaC14H16N2O8S2
Cas No.57757-57-0
SmilesO(C(CCSSCCC(ON1C(=O)CCC1=O)=O)=O)N2C(=O)CCC2=O
Relative Density.1.57 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90 mg/mL (222.54 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4727 mL12.3634 mL24.7268 mL123.6338 mL
5 mM0.4945 mL2.4727 mL4.9454 mL24.7268 mL
10 mM0.2473 mL1.2363 mL2.4727 mL12.3634 mL
20 mM0.1236 mL0.6182 mL1.2363 mL6.1817 mL
50 mM0.0495 mL0.2473 mL0.4945 mL2.4727 mL
100 mM0.0247 mL0.1236 mL0.2473 mL1.2363 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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