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9-deoxy-9-methylene Prostaglandin E2

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Catalog No. T36728Cas No. 61263-32-9
Alias 9-deoxy-9-methylene Prostaglandin E2

9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2 that retains its biological profile with fewer side effects. In rats, it is equipotent to PGE2 in decreasing blood pressure and stimulates the gerbil colon and primate uterus with the same potency as PGE2.

9-deoxy-9-methylene Prostaglandin E2

9-deoxy-9-methylene Prostaglandin E2

😃Good
Catalog No. T36728Alias 9-deoxy-9-methylene Prostaglandin E2Cas No. 61263-32-9
9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2 that retains its biological profile with fewer side effects. In rats, it is equipotent to PGE2 in decreasing blood pressure and stimulates the gerbil colon and primate uterus with the same potency as PGE2.
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Product Introduction

Bioactivity
Description
9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2 that retains its biological profile with fewer side effects. In rats, it is equipotent to PGE2 in decreasing blood pressure and stimulates the gerbil colon and primate uterus with the same potency as PGE2.
Alias9-deoxy-9-methylene Prostaglandin E2
Chemical Properties
Molecular Weight350.499
FormulaC21H34O4
Cas No.61263-32-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: >100 mg/mL (from PGE2), Sonication is recommended.
DMF: >100 mg/mL (from PGE2), Sonication is recommended.
Ethanol: >100 mg/mL (from PGE2), Sonication is recommended.
PBS (pH 7.2): >5 mg/mL (from PGE2), Sonication is recommended.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

9 deoxy 9 methylene Prostaglandin E29deoxy9methylene Prostaglandin E29-deoxy-9-methylene Prostaglandin E-2
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