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Dehydronitrosonisoldipine

🥰Excellent
Catalog No. T10991Cas No. 87375-91-5

Dehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders. Dehydronitrosonisoldipine inhibits axon degenration and the Vincristine-activated cADPR production in neurons.

Dehydronitrosonisoldipine

Dehydronitrosonisoldipine

🥰Excellent
Purity: 98.02%
Catalog No. T10991Cas No. 87375-91-5
Dehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders. Dehydronitrosonisoldipine inhibits axon degenration and the Vincristine-activated cADPR production in neurons.
Pack SizePriceAvailabilityQuantity
1 mg$48In Stock
2 mg$73In Stock
5 mg$133In Stock
10 mg$187In Stock
25 mg$322In Stock
50 mg$459In Stock
100 mg$592In Stock
500 mg$1,180In Stock
1 mL x 10 mM (in DMSO)$131In Stock
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Purity:98.02%
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Product Introduction

Bioactivity
Description
Dehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders. Dehydronitrosonisoldipine inhibits axon degenration and the Vincristine-activated cADPR production in neurons.
In vitro
Dehydronitrosonisoldipine exhibits an IC50 of 4 μM in the sterile α and TIR motif-containing 1-dN-expression cells, and decreases the cellular cADPR[1].
Chemical Properties
Molecular Weight370.4
FormulaC20H22N2O5
Cas No.87375-91-5
SmilesCOC(=O)c1c(C)nc(C)c(C(=O)OCC(C)C)c1-c1ccccc1N=O
Relative Density.1.20 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90 mg/mL (243 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6998 mL13.4989 mL26.9978 mL134.9892 mL
5 mM0.5400 mL2.6998 mL5.3996 mL26.9978 mL
10 mM0.2700 mL1.3499 mL2.6998 mL13.4989 mL
20 mM0.1350 mL0.6749 mL1.3499 mL6.7495 mL
50 mM0.0540 mL0.2700 mL0.5400 mL2.6998 mL
100 mM0.0270 mL0.1350 mL0.2700 mL1.3499 mL

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