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15(R)-15-methyl PGF2α, a metabolically stable analog of PGF2α, is an inactive, prodrug PGF agonist intended for activation by gastric acid through oral administration. This transformation involves acid-catalyzed epimerization that converts 15(R)-15-methyl PGF2α into its active counterpart, the 15(S)-isomer. Upon conversion, the 15(S)-isomer has been shown to induce luteolysis in rhesus monkeys following an approximately 12 mg/animal dosage, a response not observed with the 15(R)-isomer.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 8-10 weeks | |
50 mg | Inquiry | 8-10 weeks |
Description | 15(R)-15-methyl PGF2α, a metabolically stable analog of PGF2α, is an inactive, prodrug PGF agonist intended for activation by gastric acid through oral administration. This transformation involves acid-catalyzed epimerization that converts 15(R)-15-methyl PGF2α into its active counterpart, the 15(S)-isomer. Upon conversion, the 15(S)-isomer has been shown to induce luteolysis in rhesus monkeys following an approximately 12 mg/animal dosage, a response not observed with the 15(R)-isomer. |
Alias | 15(R)-15-methyl PGF2α |
Molecular Weight | 368.514 |
Formula | C21H36O5 |
Cas No. | 35864-81-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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