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ROS-generating agent 1

🥰Excellent
Catalog No. T77762Cas No. 2369030-41-9

Ros-generating agent 1 has anticancer activity and generates ROS by covalently modifying Sec-498 residues of TrxR. ROS-generating agent 1 reduces intracellular TrxR protein levels and promotes ROs-dependent apoptosis and ferroptosis in NCI-H460 cells.

ROS-generating agent 1

ROS-generating agent 1

🥰Excellent
Purity: 99.67%
Catalog No. T77762Cas No. 2369030-41-9
Ros-generating agent 1 has anticancer activity and generates ROS by covalently modifying Sec-498 residues of TrxR. ROS-generating agent 1 reduces intracellular TrxR protein levels and promotes ROs-dependent apoptosis and ferroptosis in NCI-H460 cells.
Pack SizePriceAvailabilityQuantity
1 mg$31In Stock
5 mg$72In Stock
10 mg$122In Stock
25 mg$198In Stock
50 mg$372In Stock
100 mg$622In Stock
500 mg$1,280In Stock
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Purity:99.67%
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Product Introduction

Bioactivity
Description
Ros-generating agent 1 has anticancer activity and generates ROS by covalently modifying Sec-498 residues of TrxR. ROS-generating agent 1 reduces intracellular TrxR protein levels and promotes ROs-dependent apoptosis and ferroptosis in NCI-H460 cells.
Chemical Properties
Molecular Weight411.34
FormulaC21H15F6NO
Cas No.2369030-41-9
SmilesC(=C\1/C(=O)\C(=C\C2=CC(C(F)(F)F)=CC=C2)\CNC1)\C3=CC(C(F)(F)F)=CC=C3
Relative Density.1.363 g/cm3 at 20℃ (Predicted)
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (109.4 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4311 mL12.1554 mL24.3108 mL121.5539 mL
5 mM0.4862 mL2.4311 mL4.8622 mL24.3108 mL
10 mM0.2431 mL1.2155 mL2.4311 mL12.1554 mL
20 mM0.1216 mL0.6078 mL1.2155 mL6.0777 mL
50 mM0.0486 mL0.2431 mL0.4862 mL2.4311 mL
100 mM0.0243 mL0.1216 mL0.2431 mL1.2155 mL

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