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Atherosperminine
Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine exerts a non-specific relaxant effect on the trachealis, its major mechanism of action appears to be inhibition of cAMP phosphodiesterase.
Catalog No. TN3466Cas No. 5531-98-6
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Purity:99.4%
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Atherosperminine
Catalog No. TN3466Cas No. 5531-98-6
Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine exerts a non-specific relaxant effect on the trachealis, its major mechanism of action appears to be inhibition of cAMP phosphodiesterase.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $95 | In Stock | |
| 2 mg | $143 | In Stock | |
| 5 mg | $219 | In Stock | |
| 10 mg | $329 | In Stock | |
| 25 mg | $562 | In Stock | |
| 50 mg | $790 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $222 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
| Description | Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine shows strong anti-plasmodial activity against Plasmodium falciparum, with the IC50 value of 5.80 uM, it also s |
| Targets&IC50 | DPPH:54.53 ug/mL, Anti-plasmodial:5.80 μM |
| In vitro | Atherosperminine shows strong anti-plasmodial activity against Plasmodium falciparum, with the IC50 value of 5.80 μM. Atherosperminine also shows antioxidant activity in a DPPH assay with the IC50 value of 54.53 ug/mL[3]. |
| Molecular Weight | 309.4 |
| Formula | C20H23NO2 |
| Cas No. | 5531-98-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (161.6 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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