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Adiphenine hydrochloride

Catalog No. T0072Cas No. 50-42-0
Alias Spasnil, Sentiv, Patrovina, Adiphenine HCl

Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.

Adiphenine hydrochloride

Adiphenine hydrochloride

Purity: 99.76%
Catalog No. T0072Alias Spasnil, Sentiv, Patrovina, Adiphenine HClCas No. 50-42-0
Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.
Pack SizePriceAvailabilityQuantity
50 mg$39In Stock
100 mg$57In Stock
200 mg$83In Stock
500 mg$138In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:99.76%
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Product Introduction

Bioactivity
Description
Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.
Targets&IC50
α1 nAChR:1.9 µM (IC50), α4β2 nAChR:3.7 µM (IC50), α4β4 nAChR:6.3 µM (IC50), α3β4 nAChR:1.8 µM (IC50)
AliasSpasnil, Sentiv, Patrovina, Adiphenine HCl
Chemical Properties
Molecular Weight347.88
FormulaC20H25NO2·HCl
Cas No.50-42-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (143.73 mM)
H2O: 64 mg/mL (184 mM)
Ethanol: 15 mg/mL (43.1 mM)
Solution Preparation Table
Ethanol/DMSO/H2O
1mg5mg10mg50mg
1 mM2.8746 mL14.3728 mL28.7455 mL143.7277 mL
5 mM0.5749 mL2.8746 mL5.7491 mL28.7455 mL
10 mM0.2875 mL1.4373 mL2.8746 mL14.3728 mL
20 mM0.1437 mL0.7186 mL1.4373 mL7.1864 mL
DMSO/H2O
1mg5mg10mg50mg
50 mM0.0575 mL0.2875 mL0.5749 mL2.8746 mL
100 mM0.0287 mL0.1437 mL0.2875 mL1.4373 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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