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Anti-Parkinson's Disease Compound Library

Catalog No. L9830
  Library Compound List   Excel SDF

Parkinson's disease (PD), the most common neurodegenerative movement disorder, is characterized by an extensive and progressive loss of dopaminergic neurons in the substantia nigra pars compacta. The incidence of PD is 1 percent of the population over the age of 60. This increases to 5 percent of the population over age 85. This makes aging is the biggest risk factor for developing PD. Parkinson’s disease symptoms include muscle rigidity, tremors, and changes in speech and gait. PD also had more severe insomnia and more symptoms of depression. The cause of PD is not known, but a number of genetic risk factors have now been characterized, as well as several genes which cause rare familial forms of PD. Environmental influences such as smoking, caffeine consumption, and pesticide exposure have been postulated to alter the risk of PD development, although the role of these remains unclear. PD is a multifactorial disease, with both genetic and environmental factors playing a role. Currently PD cannot be cured. Treatment predominantly focuses on symptomatic relief with drugs aiming to either restore the level of dopamine in the striatum or to act on striatal post-synaptic dopamine receptors, but none has yet been shown to slow the progression of the disease in humans.

Available drugs for PD include Levodopa, monoamine oxidase inhibitors (MAOIs), dopamine agonists, Glutamate antagonist, the putative N-meihyl-o-aspartaie (NMDA) receptor antagonists, COMT inhibitors, Anticholinergics, and the muscarinic receptor blockers, etc. 

TargetMol’s Anti-Parkinson's Disease Compound Library, containing 908 compounds with anti-PD activities or acting on main drug targets of PD, can be used for related drug discovery and pharmacology research.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
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Product Description

  • A unique collection of 908 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.
  • Targets include Dopamine Receptor, COMT, MAO-B, 5-HT Receptor, etc.
  • Some of them are FDA approved. 
  • Structurally diverse, medicinally active, and cell permeable;
  • Detailed information about compound structure, target, activity, IC50, etc.
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Library Customization

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Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L9830)

Library Composition

5-HT Receptor (237)
Dopamine Receptor (152)
AChR (122)
GABA Receptor (93)
Opioid Receptor (64)
NMDAR (44)
Adrenergic Receptor (40)
Histamine Receptor (39)
GluR (27)
Norepinephrine (21)
LRRK2 (18)
MAO (17)
Adenosine Receptor (13)
Calcium Channel (11)
Potassium Channel (10)
P450 (9)
Bcr-Abl (9)
Sodium Channel (8)
ROS (8)
Transferase (6)
Apoptosis (6)
Endogenous Metabolite (6)
Dehydrogenase (5)
BCL (4)
Aurora Kinase (4)
COX (4)
Mitochondrial Metabolism (4)
Autophagy (4)
Histone Methyltransferase (3)
PI3K (3)
PARP (3)
IκB/IKK (3)
FLT (3)
NOS (3)
Sigma receptor (3)
NF-κB (3)
Chloride channel (3)
Src (3)
TNF (3)
Caspase (3)
Antifection (2)
Antifungal (2)
Beta Amyloid (2)
JNK (2)
JAK (2)
Antibacterial (2)
CaMK (2)
IL Receptor (2)
p53 (2)
Parasite (2)
Carbonic Anhydrase (2)
PDE (2)
MMP (2)
EGFR (2)
CDK (2)
c-Kit (2)
Estrogen/progestogen Receptor (2)
Serotonin Transporter (2)
HDAC (2)
RAAS (1)
SGLT (1)
Vitamin (1)
Tyrosinase (1)
NOD (1)
TRP/TRPV Channel (1)
Trk receptor (1)
Na-K-Cl cotransporter (1)
Syk (1)
RAR/RXR (1)
TGF-beta/Smad (1)
Prostaglandin Receptor (1)
S6 Kinase (1)
Rho (1)
Transaminase (1)
P2 Receptor (1)
transporter (1)
Reactive Oxygen Species (1)
Phospholipase (1)
Hydroxylase (1)
mTOR (1)
DNA/RNA Synthesis (1)
Glucocorticoid Receptor (1)
GluCls (1)
Gamma-secretase (1)
FGFR (1)
FAAH (1)
Epigenetic Reader Domain (1)
DYRK (1)
DNA Alkylation (1)
GPR (1)
Decarboxylase (1)
c-Met/HGFR (1)
CCR (1)
Cannabinoid Receptor (1)
Annexin A (1)
Androgen Receptor (1)
Amino Acids and Derivatives (1)
AChE (1)
Glucokinase (1)
GRK (1)
MRP (1)
iGluR (1)
Monoamine Transporter (1)
MLK (1)
Microtubule Associated (1)
MEK (1)
Mdm2 (1)
MAPK (1)
Lipoxygenase (1)
IGF-1R (1)
GST (1)
IAP (1)
ABC (1)
HSP (1)
HMG-CoA Reductase (1)
HIV Protease (1)
Histone Demethylase (1)
HER (1)
HCV Protease (1)
Wnt/beta-catenin (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE