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(+)-Sparteine
Catalog No. T7853Cas No. 492-08-0
Alias Pachycarpine
(+)-Sparteine is a quinoline alkaloid extracted from Scotch broom, a sodium channel blocker and a class 1a antiarrhythmic agent. It competitively inhibits the activity of nicotinic acetylcholine receptors in nerve cells and is a ganglionic blocking agent.
(+)-Sparteine
Catalog No. T7853Alias PachycarpineCas No. 492-08-0
(+)-Sparteine is a quinoline alkaloid extracted from Scotch broom, a sodium channel blocker and a class 1a antiarrhythmic agent. It competitively inhibits the activity of nicotinic acetylcholine receptors in nerve cells and is a ganglionic blocking agent.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | $42 | In Stock |
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Purity:99.90%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | (+)-Sparteine is a quinoline alkaloid extracted from Scotch broom, a sodium channel blocker and a class 1a antiarrhythmic agent. It competitively inhibits the activity of nicotinic acetylcholine receptors in nerve cells and is a ganglionic blocking agent. |
| In vitro | (+)-Sparteine (Pachycarpine) (2 μM) reduces ACh-induced currents caused by activation of nicotinic ACh receptors (AChRs) in a voltage-independent manner at membrane potentials between -50 mV and +30 mV; the ACh dose-response relationship is altered by 2 μM (+)-Sparteine (Pachycarpine) at -50 mV and -90 mV in a manner typical of a competitive but not competitive antagonist. [1] |
| Alias | Pachycarpine |
| Molecular Weight | 234.38 |
| Formula | C15H26N2 |
| Cas No. | 492-08-0 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 5 mg/mL (21.3 mM), Sonication is recommended.  H2O: 2.86 mg/mL (12.20 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
H2O/DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
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