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Pilocarpine Hydrochloride

Pilocarpine Hydrochloride
Pilocarpine Hydrochloride (NSC 5746 HCl) , a nonselective muscarinic acetylcholine receptor agonist, is utilized to produce an experimental model of epilepsy.
Catalog No. T0804Cas No. 54-71-7
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Purity:99.96%
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Pilocarpine Hydrochloride

Catalog No. T0804Alias Pilocarpine HCl, NSC 5746 HCl, (+)-Pilocarpine hydrochlorideCas No. 54-71-7

Pilocarpine Hydrochloride (NSC 5746 HCl) , a nonselective muscarinic acetylcholine receptor agonist, is utilized to produce an experimental model of epilepsy.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
100 mg$54In Stock
500 mg$87In Stock
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Product Introduction

Bioactivity
Description
Pilocarpine Hydrochloride (NSC 5746 HCl) , a nonselective muscarinic acetylcholine receptor agonist, is utilized to produce an experimental model of epilepsy.
In vivo
In the parasympathetic nervous system, Pilocarpine acts as a non-selective muscarinic receptor agonist, effectively targeting the muscarinic acetylcholine subtype M3 receptors.
AliasPilocarpine HCl, NSC 5746 HCl, (+)-Pilocarpine hydrochloride
Chemical Properties
Molecular Weight244.72
FormulaC11H16N2O2·HCl
Cas No.54-71-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 24.5 mg/mL (100 mM)
DMSO: 4.62 mg/mL (18.86 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM4.0863 mL20.4315 mL40.8630 mL204.3151 mL
5 mM0.8173 mL4.0863 mL8.1726 mL40.8630 mL
10 mM0.4086 mL2.0432 mL4.0863 mL20.4315 mL
H2O
1mg5mg10mg50mg
20 mM0.2043 mL1.0216 mL2.0432 mL10.2158 mL
50 mM0.0817 mL0.4086 mL0.8173 mL4.0863 mL
100 mM0.0409 mL0.2043 mL0.4086 mL2.0432 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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