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Nobiletin

Nobiletin
Nobiletin (Hexamethoxyflavone) is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor activities. Nobiletin is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa).
Catalog No. T2834Cas No. 478-01-3
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Purity:98.88%
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Nobiletin

Catalog No. T2834Alias HexamethoxyflavoneCas No. 478-01-3

Nobiletin (Hexamethoxyflavone) is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor activities. Nobiletin is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
5 mg$52In Stock
10 mg$81In Stock
25 mg$126In Stock
50 mg$171In Stock
100 mg$279In Stock
200 mg$413In Stock
500 mg$688In Stock
1 mL x 10 mM (in DMSO)$54In Stock
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Product Introduction

Bioactivity
Description
Nobiletin (Hexamethoxyflavone) is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor activities. Nobiletin is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa).
In vivo
LD50: 780 mg/kg (i.g.). [4]
AliasHexamethoxyflavone
Chemical Properties
Molecular Weight402.39
FormulaC21H22O8
Cas No.478-01-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 3 mg/mL (7.45 mM)
DMSO: 70 mg/mL (173.96 mM)
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM2.4852 mL12.4258 mL24.8515 mL124.2576 mL
5 mM0.4970 mL2.4852 mL4.9703 mL24.8515 mL
DMSO
1mg5mg10mg50mg
10 mM0.2485 mL1.2426 mL2.4852 mL12.4258 mL
20 mM0.1243 mL0.6213 mL1.2426 mL6.2129 mL
50 mM0.0497 mL0.2485 mL0.4970 mL2.4852 mL
100 mM0.0249 mL0.1243 mL0.2485 mL1.2426 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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