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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $155 | 35 days | |
5 mg | $675 | 35 days | |
10 mg | $1,190 | 35 days |
Description | A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists. 17-trifluoromethylphenyl trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trinor PGF2α would act very much like the free acid of travoprost. 17-phenyl trinor PGF2α is a potent luteolytic and abortifacient, with a potency equal to or greater than fluprostenol and cloprostenol. |
Alias | 17-trifluoromethylphenyl trinor Prostaglandin F2α |
Molecular Weight | 456.502 |
Formula | C24H31F3O5 |
Cas No. | 221246-34-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMSO: 25 mg/mL PBS (pH 7.2): 1 mg/mL DMF: 30 mg/mL Ethanol: 50 mg/mL |
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