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Dehydroepiandrosterone sulfate

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Purity:98.05%

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COA HPLC HNMR

Dehydroepiandrosterone sulfate

Catalog No. T26366Cas No. 651-48-9

Dehydroepiandrosterone sulfate (PB-005) influences the migration of neurons, arborization of dendrites, and formation of new synapses.

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Pack Size	Price	Availability
1 mg	$40	In Stock
5 mg	$89	In Stock
10 mg	$147	In Stock
25 mg	$297	In Stock
50 mg	$472	In Stock
100 mg	$690	In Stock
1 mL x 10 mM (in DMSO)	$97	In Stock

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Product Introduction

Bioactivity

Description	Dehydroepiandrosterone sulfate (PB-005) influences the migration of neurons, arborization of dendrites, and formation of new synapses.
In vitro	Dehydroepiandrosterone sulfate selectively increases the length of neurites containing the dendritic marker MAP-2 and increases neuronal excitability when directly applied to septal-preoptic neurons[1].
In vivo	Chronic administration of Dehydroepiandrosterone sulfate produces a dose-dependent effect on performance. In male Sprague-Dawley rats, Dehydroepiandrosterone sulfate (5-20 mg/kg; s.c.) is significantly effective in improving latency to reach the platform[3].
Alias	PB 005, PB005, Prasterone sulfate, DHEA sulfate, DHEAS, PB-005

Chemical Properties

Molecular Weight	368.49
Formula	C19H28O5S
Cas No.	651-48-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 91.8 mg/mL (249.1 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7138 mL	13.5689 mL	27.1378 mL	135.6889 mL
5 mM	0.5428 mL	2.7138 mL	5.4276 mL	27.1378 mL
10 mM	0.2714 mL	1.3569 mL	2.7138 mL	13.5689 mL
20 mM	0.1357 mL	0.6784 mL	1.3569 mL	6.7844 mL
50 mM	0.0543 mL	0.2714 mL	0.5428 mL	2.7138 mL
100 mM	0.0271 mL	0.1357 mL	0.2714 mL	1.3569 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Dehydroepiandrosterone SulfateDHEA SulfatePrasterone Sulfate

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