Popular Searches
Diphenyleneiodonium chlorideEpacadostatGilteritinibDinaciclibRo-3306
TargetMol | Star Product
Wikimole
TargetMol | New Product
New Product
TargetMol | Compound Library
Compound Library
Contact Us
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
TOPBioactivityChemical infoStorage&SolubilityCalculator

2-Isopropylmalic acid

🥰Excellent
Catalog No. TN6937Cas No. 3237-44-3
Alias α-Isopropylmalate, α-IPM, 2-hydroxy-2-(propan-2-yl)butanedioic acid

2-Isopropylmalic acid (α-Isopropylmalate) inhibits excess reactive oxygen species (ROS) production and stress kinase activation in PM2. 5-treated dermal fibroblasts, promotes primary ciliogenesis and restores PM2. 5-induced primary ciliogenesis hypoplasia in dermal fibroblasts.

2-Isopropylmalic acid

2-Isopropylmalic acid

🥰Excellent
Catalog No. TN6937Alias α-Isopropylmalate, α-IPM, 2-hydroxy-2-(propan-2-yl)butanedioic acidCas No. 3237-44-3
2-Isopropylmalic acid (α-Isopropylmalate) inhibits excess reactive oxygen species (ROS) production and stress kinase activation in PM2. 5-treated dermal fibroblasts, promotes primary ciliogenesis and restores PM2. 5-induced primary ciliogenesis hypoplasia in dermal fibroblasts.
Pack SizePriceAvailabilityQuantity
1 mg$43In Stock
5 mg$94In Stock
10 mg$136In Stock
25 mg$225In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "2-Isopropylmalic acid"

Select Batch
Contact us for more batch information
Resource Download
COA HNMR
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
2-Isopropylmalic acid (α-Isopropylmalate) inhibits excess reactive oxygen species (ROS) production and stress kinase activation in PM2. 5-treated dermal fibroblasts, promotes primary ciliogenesis and restores PM2. 5-induced primary ciliogenesis hypoplasia in dermal fibroblasts.
In vitro
500 μM 2-Isopropylmalic acid promoted LEU3 protein (Leu3p)-dependent transcriptional activity.[1]
In preadipocytes (30A5), 10 mM 2-Isopropylmalic acid elevated the expression level of the reporter gene after 48 hours of action. [2]
Aliasα-Isopropylmalate, α-IPM, 2-hydroxy-2-(propan-2-yl)butanedioic acid
Chemical Properties
Molecular Weight176.17
FormulaC7H12O5
Cas No.3237-44-3
SmilesO=C(O)CC(O)(C(=O)O)C(C)C
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 200 mg/mL (1135.27 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM5.6763 mL28.3817 mL56.7634 mL283.8168 mL
5 mM1.1353 mL5.6763 mL11.3527 mL56.7634 mL
10 mM0.5676 mL2.8382 mL5.6763 mL28.3817 mL
20 mM0.2838 mL1.4191 mL2.8382 mL14.1908 mL
50 mM0.1135 mL0.5676 mL1.1353 mL5.6763 mL
100 mM0.0568 mL0.2838 mL0.5676 mL2.8382 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

2-Isopropylmalic acid2Isopropylmalic acid2 Isopropylmalic acid
Related Tags: buy 2-Isopropylmalic acid | purchase 2-Isopropylmalic acid | 2-Isopropylmalic acid cost | order 2-Isopropylmalic acid | 2-Isopropylmalic acid chemical structure | 2-Isopropylmalic acid in vitro | 2-Isopropylmalic acid formula | 2-Isopropylmalic acid molecular weight
TargetMol | Logo

Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.