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Sylvestroside I may have analgesic effect.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | 418 € | Backorder | |
1 mL x 10 mM (in DMSO) | 437 € | Backorder |
Description | Sylvestroside I may have analgesic effect. |
In vitro | The isolation of five iridoids and bis-iridoids identified as secologanin (I), swerosidic acid (II), secoxyloganin (III), Sylvestroside I (IV) and Sylvestroside III (V) from Acicarpha tribuloides Juss. (Calyceraceae). Also, the pharmacological profile of the extracts (Petroleum ether, CHCl 3, CHCl 3 /MeOH (9:1), MeOH and n-BuOH) from A. tribuloides was studied both in vivo and in vitro experiments. The in vivo experiments indicate that CHCl 3 /MeOH, MeOH and n-BuOH (100, 50 and 10 mg/kg/po) induce a significative analgesic effect in mice whereas CHCl 3 and petroleum ether extracts were inactive. In the in vitro experiments the extracts showed a similar activity because CHCl 3 /MeOH, MeOH and n-BuOH (500,250 and 125 μg/ml) were able to reduce the electrically induced contractions of guinea-pig ileum whereas CHCl 3 and petroleum ether extracts did not. |
Molecular Weight | 748.72 |
Formula | C33H48O19 |
Cas No. | 71431-22-6 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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