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Tephrosin

Name: Tephrosin
Brand: TargetMol
SKU: T13126
Rating: 4.5 (1 reviews)

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Catalog No. T13126Cas No. 76-80-2

Alias Hydroxydeguelin, Deguelinol I

Tephrosin induces degradation of of EGFR and ErbB2 by inducing internalization of the receptors, has potent antitumor activities.

Tephrosin

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Catalog No. T13126Alias Hydroxydeguelin, Deguelinol ICas No. 76-80-2

Tephrosin induces degradation of of EGFR and ErbB2 by inducing internalization of the receptors, has potent antitumor activities.

Pack Size	Price	Availability	Quantity
5 mg	930 €	Backorder

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Product Introduction

Bioactivity

Description	Tephrosin induces degradation of of EGFR and ErbB2 by inducing internalization of the receptors, has potent antitumor activities.
In vitro	Tephrosin (0-10μM) inhibits both the ligand-induced and constitutive phosphorylation of EGFR, ErbB2 and ErbB3, and concomitantly suppresses the activation of the downstream signaling molecules such as Akt and Erk1/2 mitogen-activated protein kinase (MAPK) in HT-29 cells.
Alias	Hydroxydeguelin, Deguelinol I

Chemical Properties

Molecular Weight	410.42
Formula	C₂₃H₂₂O₇
Cas No.	76-80-2
Relative Density.	1.2284 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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Keywords

Tephrosin