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Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group produces 15-keto-17-phenyl trinor PGF2α ethyl amide. 15-keto-17-phenyl trinor PGF2α ethyl amide is a potential metabolite of 17-phenyl trinor PGF2α ethyl amide when 17-phenyl trinor PGF2α ethyl amide is administered to intact animals. No pharmacological studies on 15-keto-17-phenyl trinor PGF2α ethyl amide have been reported.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $170 | 35 days | |
5 mg | $755 | 35 days | |
10 mg | $1,330 | 35 days | |
25 mg | $2,920 | 35 days |
Description | Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group produces 15-keto-17-phenyl trinor PGF2α ethyl amide. 15-keto-17-phenyl trinor PGF2α ethyl amide is a potential metabolite of 17-phenyl trinor PGF2α ethyl amide when 17-phenyl trinor PGF2α ethyl amide is administered to intact animals. No pharmacological studies on 15-keto-17-phenyl trinor PGF2α ethyl amide have been reported. |
Alias | 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide |
Molecular Weight | 413.558 |
Formula | C25H35NO4 |
Cas No. | 1163135-96-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
Solubility Information | PBS (pH 7.2): 0.5 mg/mL (1.21 mM), Sonication is recommended. Ethanol: 10 mg/mL (24.18 mM), Sonication is recommended. DMF: 2.5 mg/mL (6.05 mM), Sonication is recommended. DMSO: 2 mg/mL (4.84 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
PBS (pH 7.2)/DMSO/DMF/Ethanol
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