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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $153 | 35 days | |
5 mg | $660 | 35 days | |
10 mg | $1,170 | 35 days | |
50 mg | $4,650 | 35 days |
Description | Unoprostone is a prostaglandin F2α analogs (PGAs), and reduces intraocular pressure and is used topically for glaucoma or ocular hypertension. |
In vitro | Pretreatment with Unoprostone (0.01, 0.1, 1 μM; 1 hour before H2O2 treatment) prevents H2O2-induced cell death in a concentration-dependent manner, and the effect is significant at 0.1 μM and 1 μM concentrations[1]. Pretreatment with Unoprostone at a concentration of 0.1 to 3 μM can prevent light-induced cell death in a concentration-dependent manner; the effect is significant at 1 and 3 μM. Unoprostone reduces the morphological change, and it significantly inhibits the low mitochondrial membrane potential and cell death induced by light irradiation[1]. Unoprostone has prostaglandin F2α receptors (FP) binding affinity (Ki of 3.86 μM)[2]. |
Molecular Weight | 382.53 |
Formula | C22H38O5 |
Cas No. | 120373-36-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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