Shopping Cart
- Remove All
Your shopping cart is currently empty
Unoprostone
😃Good
Catalog No. T13955Cas No. 120373-36-6
Unoprostone is a prostaglandin F2α analogs (PGAs), and reduces intraocular pressure and is used topically for glaucoma or ocular hypertension.
Unoprostone
😃Good
Catalog No. T13955Cas No. 120373-36-6
Unoprostone is a prostaglandin F2α analogs (PGAs), and reduces intraocular pressure and is used topically for glaucoma or ocular hypertension.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $153 | 35 days | |
| 5 mg | $660 | 35 days | |
| 10 mg | $1,170 | 35 days | |
| 50 mg | $4,650 | 35 days |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Unoprostone is a prostaglandin F2α analogs (PGAs), and reduces intraocular pressure and is used topically for glaucoma or ocular hypertension. |
| In vitro | Pretreatment with Unoprostone (0.01, 0.1, 1 μM; 1 hour before H2O2 treatment) prevents H2O2-induced cell death in a concentration-dependent manner, significantly at 0.1 μM and 1 μM concentrations[1]. Similarly, Unoprostone at 0.1 to 3 μM prevents light-induced cell death, significantly at 1 and 3 μM, reduces morphological changes, and inhibits light-induced low mitochondrial membrane potential and cell death[1]. Unoprostone also exhibits binding affinity to prostaglandin F2α receptors (FP) with a Ki of 3.86 μM[2]. |
| Molecular Weight | 382.53 |
| Formula | C22H38O5 |
| Cas No. | 120373-36-6 |
| Relative Density. | 1.069g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Unoprostone | purchase Unoprostone | Unoprostone cost | order Unoprostone | Unoprostone chemical structure | Unoprostone in vitro | Unoprostone formula | Unoprostone molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.