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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $160 | 35 days | |
5 mg | $686 | 35 days | |
10 mg | $1,240 | 35 days |
Description | 6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration dependent manner. However, it is about 10-fold less potent than the β-isomer and 100-fold less potent than PGI2 in eliciting the response. 6α-PGI1 exhibits an IC50 of 350 ng/ml for inhibition of ADP-induced platelet aggregation, which is nearly 900-fold higher than that observed for PGI2 (0.4 ng/ml). |
Alias | 6α-Prostaglandin I1 |
Molecular Weight | 354.487 |
Formula | C20H34O5 |
Cas No. | 62777-90-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMSO: >5 (from 6b-PGI1) Ethanol: >20 mg/mL (from 6b-PGI1) DMF: >10 (from 6b-PGI1) PBS (pH 7.2): >80 μg (from 6b-PGI1) |
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