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Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2. Ciprostene exhibits biological activity similar to PGI2, but is 30-fold less potent. In patas monkeys, ciprostene induces hypotension and causes tachycardia when administered at a dose of 0.16 μg/kg/min. In addition, ciprostene inhibits ADP-induced platelet aggregation ex vivo and in vitro with ID50 values of 9.1 μg/kg/min and 60 ng/ml, respectively.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $380 | 35 days | |
5 mg | $1,690 | 35 days | |
10 mg | $2,940 | 35 days |
Description | Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2. Ciprostene exhibits biological activity similar to PGI2, but is 30-fold less potent. In patas monkeys, ciprostene induces hypotension and causes tachycardia when administered at a dose of 0.16 μg/kg/min. In addition, ciprostene inhibits ADP-induced platelet aggregation ex vivo and in vitro with ID50 values of 9.1 μg/kg/min and 60 ng/ml, respectively. |
Molecular Weight | 771.146 |
Formula | C44H74CaO8 |
Cas No. | 81703-55-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | PBS (pH 7.2): > 0.29 μg/mL DMSO: > 16.8 mg/mL DMF: > 25 mg/mL Ethanol: > 34 mg/mL |
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