Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Necrostatin-5 (Nec-5) is a selective inhibitor of RIP1 kinase and a cell necrosis inhibitor that prevents the death of Fadd-deficient Jurkat cells treated with TNF-α with an EC50 value of 240 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 39.00 | |
10 mg | In stock | $ 64.00 | |
25 mg | In stock | $ 147.00 | |
50 mg | In stock | $ 217.00 |
Description | Necrostatin-5 (Nec-5) is a selective inhibitor of RIP1 kinase and a cell necrosis inhibitor that prevents the death of Fadd-deficient Jurkat cells treated with TNF-α with an EC50 value of 240 nM. |
Targets&IC50 | Cell necroptosis:240 nM (EC50) |
Synonyms | Nec-5 |
Molecular Weight | 383.49 |
Formula | C19H17N3O2S2 |
CAS No. | 337349-54-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.5 mg/mL (11.7 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Necrostatin-5 337349-54-9 Apoptosis NF-Κb RIP kinase Necroptosis Nec-5 inhibitor inhibit