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ICCB-19 hydrochloride

ICCB-19 hydrochloride
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Purity:99.23%
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ICCB-19 hydrochloride

Catalog No. T8931LCas No. 1803605-68-6
ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1.
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Pack SizePriceAvailabilityQuantity
5 mg$30In Stock
10 mg$48In Stock
25 mg$97In Stock
50 mg$148In Stock
100 mg$221In Stock
200 mg$329In Stock
500 mg$521In Stock
1 mL x 10 mM (in DMSO)$30In Stock
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Product Introduction

Bioactivity
Description
ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1.
AliasICCB-19 HCl(750621-52-4 free base)
Chemical Properties
Molecular Weight291.84
FormulaC12H22ClN3OS
Cas No.1803605-68-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 25 mg/mL (85.66 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4265 mL17.1327 mL34.2654 mL171.3268 mL
5 mM0.6853 mL3.4265 mL6.8531 mL34.2654 mL
10 mM0.3427 mL1.7133 mL3.4265 mL17.1327 mL
20 mM0.1713 mL0.8566 mL1.7133 mL8.5663 mL
50 mM0.0685 mL0.3427 mL0.6853 mL3.4265 mL

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