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Bimatoprost methyl ester

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Catalog No. T37945Cas No. 38315-47-8
Alias 17-phenyl trinor Prostaglandin F2α methyl ester

Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Bimatoprost methyl ester is a lipophilic analog of 17-phenyl trinor PGF2α, a potent agonist for the FP receptor. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. Esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

Bimatoprost methyl ester

Bimatoprost methyl ester

😃Good
Catalog No. T37945Alias 17-phenyl trinor Prostaglandin F2α methyl esterCas No. 38315-47-8
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Bimatoprost methyl ester is a lipophilic analog of 17-phenyl trinor PGF2α, a potent agonist for the FP receptor. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. Esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
Pack SizePriceAvailabilityQuantity
1 mg$18335 days
5 mg$79335 days
10 mg$1,43035 days
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Product Introduction

Bioactivity
Description
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Bimatoprost methyl ester is a lipophilic analog of 17-phenyl trinor PGF2α, a potent agonist for the FP receptor. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. Esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
Alias17-phenyl trinor Prostaglandin F2α methyl ester
Chemical Properties
Molecular Weight402.531
FormulaC24H34O5
Cas No.38315-47-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
PBS (pH 7.2): 0.25 mg/mL
Acetonitrile: 3 mg/mL
Ethanol: 50 mg/mL
DMSO: 25 mg/mL
DMF: 25 mg/mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

17-phenyl trinor Prostaglandin F2a methyl esterBimatoprost methyl ester17-phenyl trinor Prostaglandin F-2α methyl ester17phenyl trinor Prostaglandin F2α methyl ester17 phenyl trinor Prostaglandin F2α methyl ester
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