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S-Nitroso-N-acetyl-DL-penicillamine

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Catalog No. T12808Cas No. 67776-06-1
Alias SNAP

S-Nitroso-N-acetyl-DL-penicillamine (SNAP) is a stable inhibitor of platelet aggregation and a nitric oxide donor.

S-Nitroso-N-acetyl-DL-penicillamine

S-Nitroso-N-acetyl-DL-penicillamine

🥰Excellent
Purity: 100%
Catalog No. T12808Alias SNAPCas No. 67776-06-1
S-Nitroso-N-acetyl-DL-penicillamine (SNAP) is a stable inhibitor of platelet aggregation and a nitric oxide donor.
Pack SizePriceAvailabilityQuantity
10 mg38 €In Stock
25 mg54 €In Stock
50 mg88 €In Stock
100 mg157 €In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
S-Nitroso-N-acetyl-DL-penicillamine (SNAP) is a stable inhibitor of platelet aggregation and a nitric oxide donor.
In vitro
S-Nitroso-N-acetyl-DL-penicillamine (10 mM; 8 hours) induces approximately 80% toxicity under normoxic conditions by releasing nitric oxide (NO) after 6 hours [1]. It has a half-life of about 6 hours in isolated rat ventricular myocytes [3] and, at 100 μM for 30 minutes, causes a sustained decrease in basal pHi in these cells [3].
AliasSNAP
Chemical Properties
Molecular Weight220.25
FormulaC7H12N2O4S
Cas No.67776-06-1
SmilesCC(=O)NC(C(O)=O)C(C)(C)SN=O
Relative Density.1.4261 g/cm3 (Estimated)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 3.45 mg/mL (15.66 mM), Sonication is recommended.
DMSO: 250 mg/mL (1135.07 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM4.5403 mL22.7015 mL45.4030 mL227.0148 mL
5 mM0.9081 mL4.5403 mL9.0806 mL45.4030 mL
10 mM0.4540 mL2.2701 mL4.5403 mL22.7015 mL
DMSO
1mg5mg10mg50mg
20 mM0.2270 mL1.1351 mL2.2701 mL11.3507 mL
50 mM0.0908 mL0.4540 mL0.9081 mL4.5403 mL
100 mM0.0454 mL0.2270 mL0.4540 mL2.2701 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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