NOS-IN-1 (2-Imino-4-methylpiperidine acetate) is a potent and orally active inhibitor of NO synthase (NOS) isoforms. NOS-IN-1 exhibits IC50s of 0.1 μM, 0.2 μM, and 1.1μM for human iNOS (hiNOS), hnNOS and heNOS, respectively.

NOS-IN-3 is a potent, selective, imidamide derived NOS inhibitor with an IC 50 against iNOS of 4.6 µM, without inhibiting eNOS . NOS-IN-3 has little toxicity and can be studied in the treatment of inducible isoform involved diseases, such as septic shock .

NOS-IN-2 (Compound 4i), an imidamide-derived NOS inhibitor, exhibits high potency and selectivity, specifically inhibiting iNOS with an IC50 of 20 μM while sparing eNOS. Demonstrating minimal toxicity, it is suitable for research on inflammatory disorders [1].

ANB-NOS is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NOS1-IN-1（nNOS Inhibitor I） is a potent, selective and cell permeable nNOS inhibitor (Ki: 120 nM).NOS1-IN-1 has a Ki value of 39 μM for eNOS and 325 μM for iNOS.NOS1-IN-1 can be used for the study of neurological disorders such as cerebral palsy.

Cyanosafracin B (Cyanoquinonamine) is a compound which can be used in the synthesis of ecteinascidin ET-743 (an antitumor chemotherapy drug).

Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.

Tucidinostat (Chidamide) is an effective and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8/11 (IC50: 733/432 nM), and shows no effect on HDAC4/5/6/7/9.

Polyinosinic-polycytidylic acid (Poly(I:C)) is a double-stranded RNA (dsRNA) and a TLR3 agonist. Polyinosinic-polycytidylic acid induces natural immunity in mammals.

Adenosine monophosphate (AMP) is a purine ribonucleoside 5'-monophosphates and a key cellular metabolite in signal transduction and regulation of energy homeostasis.It has a role as an EC 3.1.3.11 (fructose-bisphosphatase) inhibitor, an EC 3.1.3.1 (alkaline phosphatase) inhibitor and an adenosine A1 receptor agonist.

α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate) is a component of bacterial polysaccharides where it plays an important role in pathogenicity.

Hederagenin-28-beta-D-glucopyranoside, a triterpenoid saponin isolated from Ilex cornuta, protects against H2O2-induced damage in cardiomyocytes.

Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation.

Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity. Panobinostat has antitumor activity and induces apoptosis and autophagy.

L-(+)-Arabinose selectively inhibits intestinal sucrase activity in a non-competitive manner, inhibiting glucose elevation caused by sucrose intake.

Raffinose (Melitriose) is an indigestible short-chain oligosaccharide, a trisaccharide composed of galactose, glucose and fructose, found in many plants. It can be hydrolyzed by α-galactosidase (α-GAL) to D-galactose and sucrose.

L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.

5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE.

Ginsenoside Rb2 (Ginsenoside C) found in species of Panax, upregulating GPR120 gene expression.

D-Mannopyranose (Mannose) is a hexose or fermentable monosaccharide and isomer of glucose from manna, the ash Fraxinus ornus and related plants.

Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.

Isomucronulatol 7-O-glucoside is a biologically active isoflavone isolated from Astragalus membranaceus.

Pseudolaric acid A-O-β-D-glucopyranoside (Pseudolaric acid A-O-beta-D-glucopyranoside) is a natural product with antibacterial, anticancer

Adenosine 5'-diphosphate (ADP) induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase.

2'-Deoxyinosine (Guanine deoxyriboside) inhibits the growth of human colon-carcinoma cell lines and is associated with purine nucleoside phosphorylase (PNP) deficiency.

Sennoside A (NSC-112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.

PALATINOSE (TNP-470) is a natural occurring disaccharide composed of alpha-1,6-linked glucose and fructose。 PALATINOSE has a beneficial effect on liver metabolic functions and might therefore be a good substitute for sucrose as a sweetener.

1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. 2. Spinosin exerts anxiolytic-like effects, and its mechanism of action appears to be modulated by GABAA and 5-HT1A receptors. 3. There was a wide brain regional tissue distribution of Spinosin. The concentrations of Spinosin in corpus striatum and hippocampus were higher than that in other areas.

iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) is a potent nitric oxide synthase (NOS) inhibitor that inhibits the NADPH oxidase activity of nNOS.

Ginsenoside Rs2 is a natural product isolated from the leaves of Panax japonicus var..

4-QUinolinecarboxamide, N-[3-[[[2-[4-(aminosulfonyl)phenyl]ethyl]amino]carbonyl]phenyl]-1,2-dihydro-2-oxo- is an amine.

Evodenoson (ATL313) is a potent and selective adenosine A2a receptor (A2aR) agonist for the treatment of eye diseases, tumors, and immune system disorders, and may be used in studies of open-angle glaucoma and blood tumors.

Apadenoson TFA is a potent adenosine A2A receptor (A2AR) agonist that can be used to improve survival in patients infected with SARS.

Gentianose is a carbohydrate reserve derived from perennial yellow gentian storage roots.

Adenosine antagonist-1 acts as an adenosine A3 receptor (AA3R) antagonist.

Adenosine receptor A1 antagonist 5 acts as an adenosine antagonist, is an oxypurine, acts as an insecticide and pest control agent, and has an inhibitory effect on elevated blood pressure.

AzoMethine-H Monosodium salt hydrate (Sodium 5-hydroxy-4-((2-hydroxybenzylidene)amino)-7-sulfonaphthalene-2-sulfonate hydrate) is a reagent used for the colorimetric determination of boron in soil, plants, composts, manure, water and nutrient solutions.

L-(-)-Mannose ((2R,3R,4S,5S)-2,3,4,5,6-pentahydroxyhexanal) is a naturally occurring non-reducing sugar commonly used as a food additive.

2'-Deoxy-2'-fluoroarabinoadenosine is a nucleoside analogue with extensive anti-tumor activity and can be used for the study of tumor diseases.

DL-Laudanosine (Laudanosine) is a recognized metabolite of atracurium and cisatracurium.

5'-Fluoro-5'-deoxyadenosine (5'-Fluoro-5'-deoxy-adenosine) is utilized commonly as a tool for studying the Actinomycete bacterium Streptomyces cattleya.

N6-(p-Hydroxyphenethyl)-Adenosine) is an adenosine analogue.

Kanosamine (3-Amino-3-deoxyglucose) is an antifungal agent produced by a Streptomyces sp.

Aloinoside B (11-o-Rhamnosylaloin B) is a glycoside from aloe vera.

Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of glaucoma and movement disorders associated with neurologic dysfunction.

2'-O-(2-azidoethyl)adenosine is a purine nucleoside analog with potential antitumor activity. The activity of 2'-O-(2-azidoethyl)adenosine was associated with inhibition of DNA synthesis and apoptosis.

2’-beta-C-Methyl inosine (2’-C-Methylinosine) is an HCV RNA polymerase inhibitor with antiviral activity and is being studied for the treatment of hepatitis C virus infection.

3'-Deoxy-3'-fluoroguanosine is a nucleoside phosphorylase inhibitor that inhibits RNA replication by binding replons. 3 '-Deoxy-3' -fluoroguanosine is used to treat viral hepatitis, cancer and other diseases.

Eurycomanol 2-O-β-D-glucopyranoside is a natural compound belonging to the class of diterpenoids, extracted from Tongkat Ali.

Adenosine N1-oxide (1-Oxoadenosine), which is found in royal jelly, inhibited the secretion of inflammatory mediators by activated macrophages and reduced lethality in lipopolysaccharide (LPS)-induced endotoxin shock.