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Crocin II

🥰Excellent
Catalog No. T3779Cas No. 55750-84-0
Alias Tricrocin, Crocin B, Crocin 2, Crocetin gentiobiosylglucosyl ester

Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expression of iNOS and caspase-3. Crocin II can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite. Crocin II has antihyperlipidemic effect, may be due to the inhibition of pancreatic lipase and crocin, and its metabolite, Crocin II , can improve hyperlipidemia. Crocin has antidepressant effects by increasing CREB, BDNF and VGF levels in hippocampus.

Crocin II

Crocin II

🥰Excellent
Purity: 99.19%
Catalog No. T3779Alias Tricrocin, Crocin B, Crocin 2, Crocetin gentiobiosylglucosyl esterCas No. 55750-84-0
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expression of iNOS and caspase-3. Crocin II can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite. Crocin II has antihyperlipidemic effect, may be due to the inhibition of pancreatic lipase and crocin, and its metabolite, Crocin II , can improve hyperlipidemia. Crocin has antidepressant effects by increasing CREB, BDNF and VGF levels in hippocampus.
Pack SizePriceAvailabilityQuantity
1 mg$44In Stock
5 mg$96In Stock
10 mg$165In Stock
25 mg$319In Stock
50 mg$479In Stock
100 mg$688In Stock
500 mg$1,420In Stock
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Purity:99.19%
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Product Introduction

Bioactivity
Description
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expression of iNOS and caspase-3. Crocin II can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite. Crocin II has antihyperlipidemic effect, may be due to the inhibition of pancreatic lipase and crocin, and its metabolite, Crocin II , can improve hyperlipidemia. Crocin has antidepressant effects by increasing CREB, BDNF and VGF levels in hippocampus.
Targets&IC50
NO production:31.3 μM (IC50)
AliasTricrocin, Crocin B, Crocin 2, Crocetin gentiobiosylglucosyl ester
Chemical Properties
Molecular Weight814.82
FormulaC38H54O19
Cas No.55750-84-0
SmilesC\C(\C=C\C=C(/C)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)=C/C=C/C=C(\C)/C=C/C=C(\C)C(=O)O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O
Relative Density.1.47 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (61.36 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2273 mL6.1363 mL12.2726 mL61.3632 mL
5 mM0.2455 mL1.2273 mL2.4545 mL12.2726 mL
10 mM0.1227 mL0.6136 mL1.2273 mL6.1363 mL
20 mM0.0614 mL0.3068 mL0.6136 mL3.0682 mL
50 mM0.0245 mL0.1227 mL0.2455 mL1.2273 mL

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