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2'-Deoxyguanosine monohydrate

🥰Excellent
Catalog No. T4715Cas No. 312693-72-4
Alias Guanine-2'-deoxyriboside

2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of DNA. 2'-Deoxyguanosine monohydrate can be converted to 8-hydroxy-deoxyguanosine (8-OHdG) due to hydroxyl radical attack at the C8 of guanine. 8-OHdG is a sensitive marker of the DNA damage This damage, if left unrepaired, has been proposed to contribute to mutagenicity and cancer promotion.

2'-Deoxyguanosine monohydrate

2'-Deoxyguanosine monohydrate

🥰Excellent
Purity: 98.9%
Catalog No. T4715Alias Guanine-2'-deoxyribosideCas No. 312693-72-4
2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of DNA. 2'-Deoxyguanosine monohydrate can be converted to 8-hydroxy-deoxyguanosine (8-OHdG) due to hydroxyl radical attack at the C8 of guanine. 8-OHdG is a sensitive marker of the DNA damage This damage, if left unrepaired, has been proposed to contribute to mutagenicity and cancer promotion.
Pack SizePriceAvailabilityQuantity
50 mg$41In Stock
100 mg$66In Stock
500 mg$144In Stock
1 g$202In Stock
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Purity:98.9%
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Product Introduction

Bioactivity
Description
2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of DNA. 2'-Deoxyguanosine monohydrate can be converted to 8-hydroxy-deoxyguanosine (8-OHdG) due to hydroxyl radical attack at the C8 of guanine. 8-OHdG is a sensitive marker of the DNA damage This damage, if left unrepaired, has been proposed to contribute to mutagenicity and cancer promotion.
AliasGuanine-2'-deoxyriboside
Chemical Properties
Molecular Weight285.26
FormulaC10H15N5O5
Cas No.312693-72-4
SmilesO.Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1C[C@H](O)[C@@H](CO)O1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (350.5 mM), Sonication is recommended.
1 M NH4OH: 50 mg/mL
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5056 mL17.5279 mL35.0557 mL175.2787 mL
5 mM0.7011 mL3.5056 mL7.0111 mL35.0557 mL
10 mM0.3506 mL1.7528 mL3.5056 mL17.5279 mL
20 mM0.1753 mL0.8764 mL1.7528 mL8.7639 mL
50 mM0.0701 mL0.3506 mL0.7011 mL3.5056 mL
100 mM0.0351 mL0.1753 mL0.3506 mL1.7528 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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