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Castanospermine
Catalog No. TQ0308Cas No. 79831-76-8
Alias 1,6,7,8-Tetrahydroxyoctahydroindolizine, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine
Castanospermine (1,6,7,8-Tetrahydroxyoctahydroindolizine) is a natural compound that inhibits α- and β-glucosidases, especially glucosidase l.
Castanospermine
Catalog No. TQ0308Alias 1,6,7,8-Tetrahydroxyoctahydroindolizine, (1S,6S,7R,8R,8aR)-1,6,7,8-TetrahydroxyindolizidineCas No. 79831-76-8
Castanospermine (1,6,7,8-Tetrahydroxyoctahydroindolizine) is a natural compound that inhibits α- and β-glucosidases, especially glucosidase l.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $32 | In Stock | |
| 10 mg | $52 | In Stock | |
| 25 mg | Inquiry | In Stock | |
| 50 mg | Inquiry | In Stock |
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Acarbose (BAY g 5421) is an inhibitor of α-Glucosidases with antihyperglycemic activity.
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Rebaudioside A
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N-Caffeoyl O-methyltyramine
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N-Caffeoyl O-methyltyramine is isolated from Cuscuta reflexa with strong inhibitory activity against α-glucosidase with IC50 of 103.58 μM.
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1-Deoxynojirimycin Cited
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CitedNCGC00092410
ML008
T40544442898-34-2In house
NCGC00092410 (ML008) is a glucocerebrosidase (GC) inhibitor with IC50 value of 31 nM. It can be used for the study of Gaucher disease caused by mutation of glucocerebrase gene.
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Voglibose
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T672383480-29-9
Voglibose (Glustat), an N-substituted derivative of valiolamine, exhibits excellent inhibitory activity against α-glucosidases and action against hyperglycemia and various disorders caused by hyperglycemia.
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IHVR-17028
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IHVR-17028 is a potent broad-spectrum ERα-glucosidase I (α-glucosidase? I) inhibitor with IC50 of 0.24 μM and antiviral activity. IHVR-17028 inhibited BVDV, TCRV and DENV, and EC50 values were 0.4 μM, 0.26 μM and 0.3 μM, respectively. IHVR-17028 can be used to study infectious diseases.
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Conduritol B epoxide
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Conduritol B epoxide is an irreversible inhibitor of β-glucosidase (GCase).
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α-Glucosidase-IN-23
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α-Glucosidase-IN-23 is an orally active inhibitor of α-glucosidase that can decrease blood glucose levels by inhibiting α-glucosidase (IC50 = 4.48 μM).
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Pinoresinol diglucoside
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Celgosivir
MX3253, MDL 28574, MBI 3253, 6 O-butanoyl castanospermine
T10755L121104-96-9In house
Celgosivir (6 O-butanoyl castanospermine) is an inhibitor of α-glucosidase I. In vitro assay, it inhibits bovine viral diarrhoea virus (BVDV) ( IC50: 1.27 μM ).
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Purity:99.74%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Castanospermine (1,6,7,8-Tetrahydroxyoctahydroindolizine) is a natural compound that inhibits α- and β-glucosidases, especially glucosidase l. |
| In vitro | Castanospermine is a potent and specific inhibitor of mammalian and plant α-and β-D-glucosidases in vitro [1]. |
| In vivo | Experiments in vivo with castanospermine, an inhibitor of the glucosidases that convert protein N-linked high mannose carbohydrates to complex oligosaccharides, resulted in significant inhibition of tumor growth in nude mice [3]. |
| Alias | 1,6,7,8-Tetrahydroxyoctahydroindolizine, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine |
| Molecular Weight | 189.21 |
| Formula | C8H15NO4 |
| Cas No. | 79831-76-8 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 32 mg/mL (169.12 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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