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α-Glucosidase-IN-23

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Purity:99.14%

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COA HNMR HPLC LCMS

α-Glucosidase-IN-23

Catalog No. T67728Cas No. 161187-57-1

α-Glucosidase-IN-23 is an orally active α-Glucosidase inhibitor. α-Glucosidase-IN-23 can decrease blood glucose by α-glucosidase inhibition (IC50= 4.48 μM).

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Pack Size	Price	Availability
1 mg	$197	In Stock
5 mg	$478	In Stock
10 mg	$654	In Stock
25 mg	$990	In Stock
50 mg	$1,330	In Stock
100 mg	$1,750	In Stock
1 mL x 10 mM (in DMSO)	$571	In Stock

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Product Introduction

Bioactivity

Description	α-Glucosidase-IN-23 is an orally active α-Glucosidase inhibitor. α-Glucosidase-IN-23 can decrease blood glucose by α-glucosidase inhibition (IC50= 4.48 μM).
In vitro	α-Glucosidase-IN-23 (1 μM) exhibits significant anti-diabetes activity. α-Glucosidase-IN-23 decreases ROS levles in βcells and muscle cells. α-Glucosidase-IN-23 decreases blood glucose by α-glucosidase inhibition (IC50= 4.48 μM)[1].
In vivo	α- Glucosidase-IN-23 (oral; 0.2 mmol/kg/day) only inhibits α- Glucosidase in mice[1].

Chemical Properties

Molecular Weight	373.4
Formula	C20H23NO6
Cas No.	161187-57-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 25 mg/mL (66.95 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6781 mL	13.3905 mL	26.7809 mL	133.9047 mL
5 mM	0.5356 mL	2.6781 mL	5.3562 mL	26.7809 mL
10 mM	0.2678 mL	1.3390 mL	2.6781 mL	13.3905 mL
20 mM	0.1339 mL	0.6695 mL	1.3390 mL	6.6952 mL
50 mM	0.0536 mL	0.2678 mL	0.5356 mL	2.6781 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc