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5α-Hydroxycostic acid, a naturally occurring sesquiterpene, inhibits choroidal neovascularization in rats through dual signaling pathways mediated by VEGF/VEGFR and Ang2/Tie2 (angiopoietin 2), and exhibits anti-inflammatory and anti-angiogenic effects on human breast cancer cells
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $162 | In Stock | |
5 mg | $489 | Backorder |
Description | 5α-Hydroxycostic acid, a naturally occurring sesquiterpene, inhibits choroidal neovascularization in rats through dual signaling pathways mediated by VEGF/VEGFR and Ang2/Tie2 (angiopoietin 2), and exhibits anti-inflammatory and anti-angiogenic effects on human breast cancer cells |
In vitro | Methods: RCSEC cells were treated with 5α-Hydroxycostic acid (25, 50, 100 μM, 48 hours) and the inducing factor VEGF164 (30 μM) was added. Cell viability was measured by CCK8. Results: The drug had a significant effect on cell viability at concentrations above 100 μM. [1] |
Alias | 5 alpha-Hydroxycostic acid |
Molecular Weight | 250.33 |
Formula | C15H22O3 |
Cas No. | 132185-83-2 |
Smiles | O[C@]12[C@@](C)(CC[C@@H](C(C(O)=O)=C)C1)CCCC2=C |
Relative Density. | 1.12 g/cm3 (Predicted) |
Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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