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Lenvatinib mesylate
🥰Excellent
Catalog No. T8541Cas No. 857890-39-2
Alias E7080 (mesylate)
Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.
Lenvatinib mesylate
🥰Excellent
Purity: 99.79%
Catalog No. T8541Alias E7080 (mesylate)Cas No. 857890-39-2
Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $34 | In Stock | |
| 25 mg | $55 | In Stock | |
| 50 mg | $80 | In Stock | |
| 100 mg | $113 | In Stock | |
| 200 mg | $168 | In Stock | |
| 500 mg | $283 | In Stock |
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CitedSelect Batch
Purity:99.79%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities. |
| Targets&IC50 | c-Kit:100 nM, PDGFRβ:39 nM, PDGFRα:51 nM, FGFR1:46 nM, VEGFR1:22 nM, VEGFR3:5.2 nM, VEGFR2:4 nM |
| In vitro | Lenvatinib is a small-molecule tyrosine kinase inhibitor that inhibits vascular endothelial growth factor receptor (VEGFR1-3), fibroblast growth factor receptor (FGFR1-4), platelet-derived growth factor receptor α (PDGFRα), stem cell factor receptor (KIT), and rearranged during transfection (RET).?These receptors are important for tumor angiogenesis, and lenvatinib inhibits tumor angiogenesis by inhibiting function of these receptors[1]. |
| Alias | E7080 (mesylate) |
| Molecular Weight | 522.96 |
| Formula | C22H23ClN4O7S |
| Cas No. | 857890-39-2 |
| Smiles | CS(O)(=O)=O.COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 16.67 mg/mL (31.87 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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