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L-α-lysophosphatidylinositol sodium
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Catalog No. T77212Cas No. 796963-91-2
L-α-lysophosphatidylinositol sodium is an endogenous ligand of GPR55 and an endogenous cannabinoid neurotransmitter that is involved in controlling cell survival and tumor progression.
L-α-lysophosphatidylinositol sodium
L-α-lysophosphatidylinositol sodium
😃Good
Catalog No. T77212Cas No. 796963-91-2
L-α-lysophosphatidylinositol sodium is an endogenous ligand of GPR55 and an endogenous cannabinoid neurotransmitter that is involved in controlling cell survival and tumor progression.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $469 | 7-10 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | L-α-lysophosphatidylinositol sodium is an endogenous ligand of GPR55 and an endogenous cannabinoid neurotransmitter that is involved in controlling cell survival and tumor progression. |
| Targets&IC50 | murine iPSC cardiomyocytes:778 nM (EC50) |
| In vitro | Concentration‐response studies in murine iPSC cardiomyocytes demonstrated that L-α-lysophosphatidylinositol sodium‐induced DMR activity in a concentration‐dependent manner (EC50 = 778 nM) and that the time course of the DMR response was rapid in onset, reached peak activity at 10 minutes post application and persisted for the duration of the period of measurement (90 minutes). [1] |
| In vivo | Challenging WT hearts with L-α-lysophosphatidylinositol sodium prior to the onset of global ischemia significantly increased infarct size compared to vehicle controls, whereas this was not seen in seen GPR55−/− hearts, confirming an action of L-α-lysophosphatidylinositol sodium at GPR55. L-α-lysophosphatidylinositol sodium increases myocardial infarct size in hearts from wild type, but not GPR55−/−, mouse hearts. [1] |
| Molecular Weight | 594.6 |
| Formula | C25H48NaO12P |
| Cas No. | 796963-91-2 |
Storage & Solubility Information
| Storage | store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
| Solubility Information | DMSO: 4 mg/mL(6.73 mM), Sonication is recommended. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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