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Adenosine A1 receptor activator T62
🥰Excellent
Catalog No. T14127Cas No. 40312-34-3
Adenosine A1 receptor activator T62 is an allosteric enhancer of the adenosine A1 receptor, producing antinociception in animal models of acute pain and reducing hypersensitivity in models of inflammatory and nerve-injury pain[1][2][3].
Adenosine A1 receptor activator T62
🥰Excellent
Purity: 95.00%
Catalog No. T14127Cas No. 40312-34-3
Adenosine A1 receptor activator T62 is an allosteric enhancer of the adenosine A1 receptor, producing antinociception in animal models of acute pain and reducing hypersensitivity in models of inflammatory and nerve-injury pain[1][2][3].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $89 | In Stock | |
| 5 mg | $193 | In Stock | |
| 10 mg | $287 | In Stock | |
| 25 mg | $463 | In Stock | |
| 50 mg | $630 | In Stock | |
| 100 mg | $852 | In Stock | |
| 200 mg | $1,130 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $295 | In Stock |
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Purity:95.00%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Adenosine A1 receptor activator T62 is an allosteric enhancer of the adenosine A1 receptor, producing antinociception in animal models of acute pain and reducing hypersensitivity in models of inflammatory and nerve-injury pain[1][2][3]. |
| In vivo | Intrathecal administration of the adenosine A1 receptor activator T62 (0.3-3 μg) in male Sprague-Dawley rats produces a dose-dependent antihypersensitivity effect without affecting ambulation or activity levels[1]. |
| Animal Research | Intrathecal T62 of Male SpragueDawley rats (250 g) after paw incision surgery with the dose of 0.3 μg, 0.5 μg, 1 μg, and 3 μg, produced a dose-dependent antihypersensitivity effect, with no effect on ambulation or activity level. The ED40 (95% confidence interval) for T62 was 0.77 (0.63-0.91) microg. |
| Molecular Weight | 291.8 |
| Formula | C15H14ClNOS |
| Cas No. | 40312-34-3 |
| Smiles | Nc1sc2CCCCc2c1C(=O)c1ccc(Cl)cc1 |
| Relative Density. | 1.337 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 75 mg/ml (257.03 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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