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Ginsenoside Rg6
🥰Excellent
Catalog No. TN1094Cas No. 147419-93-0
Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cells
Ginsenoside Rg6
🥰Excellent
Catalog No. TN1094Cas No. 147419-93-0
Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cells
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $100 | In Stock | |
| 5 mg | $242 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $347 | In Stock |
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Purity:≥98%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Ginsenoside Rg6 can inhibit JK cell proliferation in human lymphocytoma and induce its apoptosis, the mechanism may through mitochondrial dysfunction and an increase of Bax expression and decrease of Bcl-2 expression. |
| Targets&IC50 | NF-κB:29.34 μM |
| In vitro | Ginsenoside Rg6 may inhibit the proliferation and induce apoptosis of human lymphoma JK cells through mitochondrial dysfunction and increased Bax expression and decreased Bcl-2 expression. In addition, ginsenoside Rg6 can also inhibit the transcriptional activity of NF-κB induced by TNF-α in SK-Hep1 cells with IC50 of 25uM. |
| Molecular Weight | 767 |
| Formula | C42H70O12 |
| Cas No. | 147419-93-0 |
| Smiles | [H][C@@]12[C@H](CC[C@@]1(C)[C@]1(C)C[C@H](O[C@]3([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O[C@]3([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@]3([H])C(C)(C)[C@@H](O)CC[C@]3(C)[C@@]1([H])C[C@H]2O)C(=C)CCC=C(C)C |
| Relative Density. | 1.27 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (130.38 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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