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12-O-Methylcarnosic acid

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Catalog No. TN2601Cas No. 62201-71-2

12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from Salvia microphylla, is an active constituent of 5α-Reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid has Antioxidant activity, it is effective preventing gastric lesions. 12-O-Methylcarnosic acid can suppress melanin production with downregulation of Tyrosinase expression in HMV-II melanoma cells. 12-O-Methylcarnosic acid may have anti-diabetic activity, it is able to significantly activate peroxisome proliferator-activated receptor (PPAR)γ.

12-O-Methylcarnosic acid

12-O-Methylcarnosic acid

🥰Excellent
Purity: 99.24%
Catalog No. TN2601Cas No. 62201-71-2
12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from Salvia microphylla, is an active constituent of 5α-Reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid has Antioxidant activity, it is effective preventing gastric lesions. 12-O-Methylcarnosic acid can suppress melanin production with downregulation of Tyrosinase expression in HMV-II melanoma cells. 12-O-Methylcarnosic acid may have anti-diabetic activity, it is able to significantly activate peroxisome proliferator-activated receptor (PPAR)γ.
Pack SizePriceAvailabilityQuantity
1 mg$98In Stock
5 mg$247In Stock
10 mg$397In Stock
25 mg$652In Stock
50 mg$913In Stock
100 mg$1,230In Stock
1 mL x 10 mM (in DMSO)$265In Stock
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Purity:99.24%
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Product Introduction

Bioactivity
Description
12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from Salvia microphylla, is an active constituent of 5α-Reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid has Antioxidant activity, it is effective preventing gastric lesions. 12-O-Methylcarnosic acid can suppress melanin production with downregulation of Tyrosinase expression in HMV-II melanoma cells. 12-O-Methylcarnosic acid may have anti-diabetic activity, it is able to significantly activate peroxisome proliferator-activated receptor (PPAR)γ.
Chemical Properties
Molecular Weight346.46
FormulaC21H30O4
Cas No.62201-71-2
Smiles[H][C@@]12CCc3cc(C(C)C)c(OC)c(O)c3[C@]1(CCCC2(C)C)C(O)=O
Relative Density.1.131 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 22.5 mg/mL (64.94 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8863 mL14.4317 mL28.8634 mL144.3168 mL
5 mM0.5773 mL2.8863 mL5.7727 mL28.8634 mL
10 mM0.2886 mL1.4432 mL2.8863 mL14.4317 mL
20 mM0.1443 mL0.7216 mL1.4432 mL7.2158 mL
50 mM0.0577 mL0.2886 mL0.5773 mL2.8863 mL

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