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5'-DEOXYADENOSINE

5'-DEOXYADENOSINE
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Purity:99.85%
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5'-DEOXYADENOSINE

Catalog No. T4971Cas No. 4754-39-6
5'-Deoxyadenosine (5′-dAdo) is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material, which has long been of interest in understanding the mechanism of aging, neurodegenerative diseases, and carcinogenesis. The normal form of deoxyadenosine used in DNA synthesis and repair is 2'-deoxyadenosine where the hydroxyl group (-OH) is at the 2' position of its ribose sugar moiety. 5'-deoxyadenosine has its hydroxyl group at the 5' position of the ribose sugar.
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Pack SizePriceAvailabilityQuantity
5 mg$48In Stock
10 mg$82In Stock
25 mg$166In Stock
50 mg$265In Stock
100 mg$397In Stock
1 mL x 10 mM (in DMSO)$54In Stock
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Related Compound Libraries of "5'-DEOXYADENOSINE"

Product Introduction

Bioactivity
Description
5'-Deoxyadenosine (5′-dAdo) is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material, which has long been of interest in understanding the mechanism of aging, neurodegenerative diseases, and carcinogenesis. The normal form of deoxyadenosine used in DNA synthesis and repair is 2'-deoxyadenosine where the hydroxyl group (-OH) is at the 2' position of its ribose sugar moiety. 5'-deoxyadenosine has its hydroxyl group at the 5' position of the ribose sugar.
Alias5′-dAdo
Chemical Properties
Molecular Weight251.24
FormulaC10H13N5O3
Cas No.4754-39-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
H2O: 20mg/mL
DMSO: 55 mg/mL (218.91 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.9803 mL19.9013 mL39.8026 mL199.0129 mL
5 mM0.7961 mL3.9803 mL7.9605 mL39.8026 mL
10 mM0.3980 mL1.9901 mL3.9803 mL19.9013 mL
20 mM0.1990 mL0.9951 mL1.9901 mL9.9506 mL
50 mM0.0796 mL0.3980 mL0.7961 mL3.9803 mL
100 mM0.0398 mL0.1990 mL0.3980 mL1.9901 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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