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Isolinderalactone

🥰Excellent
Catalog No. T8213Cas No. 957-66-4

Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.

Isolinderalactone

Isolinderalactone

🥰Excellent
Purity: 99.62%
Catalog No. T8213Cas No. 957-66-4
Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.
Pack SizePriceAvailabilityQuantity
1 mg$80In Stock
5 mg$197In Stock
10 mg$322In Stock
25 mg$539In Stock
50 mg$772In Stock
100 mg$1,050In Stock
1 mL x 10 mM (in DMSO)$182In Stock
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Purity:99.62%
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Product Introduction

Bioactivity
Description
Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.
Targets&IC50
iNOS:0.30 uM
In vitro
Isolinderalactone induces apoptosis in MDA-MB-231 cells and suppresses STAT3 signaling pathway through regulation of SOCS3 and miR-30c, may become a novel treatment for triple-negative breast cancer in the future.
Chemical Properties
Molecular Weight244.29
FormulaC15H16O3
Cas No.957-66-4
Smiles[H][C@@]12OC(=O)C(=C)[C@]1([H])[C@](C)(Cc1occ(C)c21)C=C
Relative Density.1.16 g/cm3 at 20℃
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 22.5 mg/mL (92.1 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0935 mL20.4675 mL40.9350 mL204.6748 mL
5 mM0.8187 mL4.0935 mL8.1870 mL40.9350 mL
10 mM0.4093 mL2.0467 mL4.0935 mL20.4675 mL
20 mM0.2047 mL1.0234 mL2.0467 mL10.2337 mL
50 mM0.0819 mL0.4093 mL0.8187 mL4.0935 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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