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3,4-O-Isopropylidene-shikimic acid

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Purity:99.47%

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COA HPLC HNMR

3,4-O-Isopropylidene-shikimic acid

Catalog No. TN1238Cas No. 183075-03-8

3,4-O-Isopropylidene-shikimic acid (3,4-O-Isopropylidene shikimic acid) has significant anti-inflammatory, anti-thrombosis, antioxidant, analgesic effects, it has protective effects on experimental colitis induced by trinitrobenzenesulfonic acid in rats, probably due to antioxidant action.

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Pack Size	Price	Availability
1 mg	$115	In Stock
5 mg	$280	In Stock
10 mg	$415	In Stock
25 mg	$689	In Stock
50 mg	$983	In Stock
100 mg	$1,330	In Stock
1 mL x 10 mM (in DMSO)	$290	In Stock

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Product Introduction

Bioactivity

Description	3,4-O-Isopropylidene-shikimic acid (3,4-O-Isopropylidene shikimic acid) has significant anti-inflammatory, anti-thrombosis, antioxidant, analgesic effects, it has protective effects on experimental colitis induced by trinitrobenzenesulfonic acid in rats, probably due to antioxidant action.
In vitro	3,4-O-Isopropylidene shikimic acid (ISA,1-100 micromol/L) effectively reduced PMN adhesion to TNF-alpha-induced HUVEC with the inhibitory rate from 17.2 % to 53.5 % and exerted no effect on PMN adhesion to normal HUVEC. Adhesion molecule ICAM-1 surface protein and mRNA expression induced by TNF-alpha (400 kU/L) were significantly inhibited by ISA. In addition, the cell viability of HUVEC was unchanged 48 h after treatment with ISA[1]
Alias	3,4-O-Isopropylidene shikimic acid

Chemical Properties

Molecular Weight	214.22
Formula	C10H14O5
Cas No.	183075-03-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/mL (280.09 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.6681 mL	23.3405 mL	46.6810 mL	233.4049 mL
5 mM	0.9336 mL	4.6681 mL	9.3362 mL	46.6810 mL
10 mM	0.4668 mL	2.3340 mL	4.6681 mL	23.3405 mL
20 mM	0.2334 mL	1.1670 mL	2.3340 mL	11.6702 mL
50 mM	0.0934 mL	0.4668 mL	0.9336 mL	4.6681 mL
100 mM	0.0467 mL	0.2334 mL	0.4668 mL	2.3340 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify

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