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Sennoside A (NSC-112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 mg | $60 | In Stock | |
1 mL x 10 mM (in DMSO) | $60 | In Stock |
Description | Sennoside A (NSC-112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine. |
Targets&IC50 | MAO:17 μM |
In vitro | Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine through regulating the spontaneous motility of colon. [2] It mildly inhibits bovine serum monoamine oxidase with IC50 of 17 μM. [1] |
In vivo | LD50: Mice 5000 mg/kg (i.g.); Rats 5000 mg/kg (i.g.). [3] |
Alias | NSC 112929 |
Molecular Weight | 862.74 |
Formula | C42H38O20 |
Cas No. | 81-27-6 |
Smiles | OC[C@H]1O[C@@H](Oc2cccc3[C@@H]([C@@H]4c5cccc(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c5C(=O)c5c(O)cc(cc45)C(O)=O)c4cc(cc(O)c4C(=O)c23)C(O)=O)[C@H](O)[C@@H](O)[C@@H]1O |
Relative Density. | 1.743g/cm3 |
Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 95 mg/mL (110.1 mM) Ethanol: < 1 mg/mL (insoluble or slightly soluble) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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